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Year : 2022  |  Volume : 12  |  Issue : 1  |  Page : 56-59

Cushing’s syndrome in a 17-year-old female teenager secondary to a unilateral right adrenal adenoma: A case report

1 Department of Internal Medicine, University of Benin/University of Benin Teaching Hospital, Benin City, Edo State, Nigeria
2 Department of Internal Medicine, Central Hospital, Benin City, Edo State, Nigeria

Correspondence Address:
Dr. Osariemen A Osunbor
Department of Internal Medicine, Central Hospital, Benin City, Edo State
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ajem.ajem_2_22

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Cushing’s syndrome is a rare endocrine disorder in the pediatric population. We report a case of a 17-year-old female Nigerian who presented with a 10 months history of progressive weight gain, amenorrhea, facial hair, and striae. She had not used oral contraceptive or steroids. Physical examination revealed an obese teenager with moon-like facies. Blood pressure was 150/90 mmHg. There were widespread striae over the back, upper arms, and thighs. The clinical diagnosis was Cushing’s syndrome. Urine free cortisol was 274.37 µg/24 h (4.3-56 µg/24 h). Plasma cortisol levels before and after dexamethasone suppression were 609.63 mmol/L and 578.71 mmol/L (normal value: <240.61 mmol/L), respectively. Plasma ACTH was 7.8 pg/mL (2.8-64.6 pg/mL). Abdominal magnetic resonance imaging (MRI) scan revealed a right adrenal mass showing mild enhancement on post-contrast. Brain MRI was normal. A right laparoscopic adrenalectomy was done. By 16 weeks post-surgery, patient’s menstrual cycle had resumed. The moon-like facies and striae were largely resolved.

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